Discussion Questions

1. Discuss the factors that can affect how quickly a drug is absorbed into the bloodstream.

2. Compare the two phases of biotransformation.

3. What is the difference between zero- and first-order kinetics?

4. Discuss the ways in which a drug might affect neurotransmission from neurotransmitter synthesis to its release to its binding of receptors.

5. Compare the various forms of tolerance described in the text.